Antimicrobial Pastes and Clinical Cases of Apexogenesis

Adriana Kelly de Sousa Santiago Barbosa

Status: Completed

Conditions: Dental Trauma; Root Canal Therapy; Apexification

Treatments: Procedure: Apexification

Study type: Interventional

Funder types: Other

Identifiers

NCT03112291

Estudo Clinico - Apicificação

Details and patient eligibility

About

The aim of this study was to perform a clinical and microbiological evaluation of teeth with incomplete apexogenesis and traumatic necrosis that were treated with a revascularization technique, evaluating the microbial reduction after the use a double antibiotic paste. Furthermore, the investigation also aims to identify the presence of Enterococcus faecalis and Porphyromomas gingivalis within the root canal system.

Full description

This investigation is a longitudinal prospective interventional study of a series of cases. Patients who sought treatment at the Faculty of Dentistry from June 2011 to September 2015 were selected. They should have one permanent tooth with traumatic necrosis.

Enrollment: 14 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• They should have one permanent tooth with traumatic necrosis, which in turns should show color alteration, fistulae, periapical lesion, and/or internal or external root resorption, pain, or absence of pulp response to sensitivity tests at a clinical examination to be considered necrotic. Male and female patients who had not undergone antibiotic therapy 3 months before the treatment were included and clinical and radiographic examinations confirmed pulp necrosis.

Exclusion criteria

• Patients who did use antibiotics
• Patients who did loss of temporary coronary sealing between treatment sessions
• Patients who give up the research

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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14 participants in 1 patient group

permanent teeth apexification

Experimental group

Description:

They should have one permanent tooth with traumatic necrosis, which in turns should show color alteration, fistulae, periapical lesion, and/or internal or external root resorption, pain, or absence of pulp response to sensitivity tests at a clinical examination to be considered necrotic. Male and female patients who had not undergone antibiotic therapy 3 months before the treatment were included and clinical and radiographic examinations confirmed pulp necrosis. This study analyzed the clinical and microbiological results of the endodontic treatment performed on permanent teeth with necrosis caused by traumatic injury and treated using revascularization technique, double antibiotic paste, intra-canal medication, and an MTA cervical plug.

Treatment:

Procedure: Apexification