Antioxidants in Gestational Diabetes

Cairo University (CU)

Status and phase: Completed; Phase 4

Conditions: Gestational Diabetes Mellitus

Treatments: Drug: L-ascorbic acid

Study type: Interventional

Funder types: Other

Identifiers

NCT02355197

124

Details and patient eligibility

About

Fasting and two hours postprandial blood sugar were done to all cases between 28 and 32 weeks and high blood sugar levels were found so Cases were controlled by both diet and insulin.

The 200 pregnant women with Gestational diabetes mellitus were randomized using automated web based randomization system into 2 groups, Group1 received 1 gram L-ascorbic acid (vitamin C )per day from the time of diagnosis until the time of delivery in addition to routine treatment of diabetes (diet & insulin). Group2 received only the treatment of diabetes

Full description

The 200 pregnant women with Gestational diabetes mellitus were randomized using automated web based randomization system into 2 groups, Group1 received 1 gram L-ascorbic acid oral once daily (vitamin C )per day from the time of diagnosis until the time of delivery in addition to routine treatment of diabetes (diet & insulin). Group2 received only the treatment of diabetes (diet and insulin

Enrollment: 200 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women with the diagnosis of GDM

Exclusion criteria

• Women with multiple pregnancies
• Chronic medical disorders e.g. anemia
• Hypertension
• Liver disease or renal disease
• Those with obstetric problems other than GDM (e.g. pre-eclampsia & antepartum hemorrhage) or smokers and women with preexisting type I or II diabetes mellitus were excluded from our study

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

200 participants in 2 patient groups

antioxidant

Active Comparator group

Description:

1 gram L-ascorbic acid (vitamin C capsule) orally once per day from the time of diagnosis until the time of delivery in addition to treatment for gestational diabetes mellitus in the form of diet and insulin

Treatment:

Drug: L-ascorbic acid

control

No Intervention group

Description:

Only treatment for gestational diabetes mellitus in the form of diet and insulin