Antiperspirant in the Treatment of Residual Limp Hyperhidrosis for Prosthetic Users

Sophies Minde Ortopedi

Status: Completed

Conditions: Residual Limbs; Hyperhidrosis

Treatments: Other: Topical antiperspirant

Study type: Interventional

Funder types: Industry

Identifiers

NCT05501444

FoU_2022_Hyperhidrosis

Details and patient eligibility

About

The aim of the present pilot study is to evaluate the effect of antiperspirant to treat residual limb hyperhidrosis with the emphasis on the utility of the iodine-starch test to identify the location of the sweating.

Full description

Many persons with lower limb amputation report that they have major problems with sweating (hyperhidrosis) on the stump in connection with prosthetic use. Despite the frequency and the negative effect of sweating for prosthetic users, there is a lack of evidence on how the sweating should be examined and treated. In the dermatological literature, the guidelines recommend the use of topical antiperspirants such as aluminum chloride as first-line treatment. No studies have previously been published evaluating the effect of antiperspirant on prosthetic users.

Enrollment: 7 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Over 18 years,
2. used a prosthetic for at least 1 year,
3. HDSS score of ≥ 2,
4. use the prosthetic daily and be able to walk for a minimum of 10 minutes.

Exclusion criteria

1. Open wounds on the stump,
2. Known sensitivity or allergy to iodine and/or starch,
3. Known sensitivity to antiperspirant.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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7 participants in 1 patient group

Effect of antiperspirant

Experimental group

Description:

Aluminium chloride 15 percent

Treatment:

Other: Topical antiperspirant