Antipsychotic Discontinuation in High-risk Subjects

Seoul National University

Status: Withdrawn

Conditions: Schizophrenia

Study type: Observational

Funder types: Other

Identifiers

NCT01758887

H-1207-055-417

Details and patient eligibility

About

• Would be there any difference in dopamine synthesis between remitted clinical high risk subjects for psychosis and healthy control?
• What would happen to dopamine synthesis after antipsychotic discontinuation in clinical high risk subjects for psychosis?
• What about the dopamine synthesis in recurred clinical high risk subjects for psychosis after the discontinuation?

Full description

After the antipsychotic medication discontinuation, we are going to assess the changes of the biological markers

Sex: All

Ages: 16 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diagnosed as a clinical High Risk
• Treated with antipsychotic drugs
• PSP1-5 (from SIPS criteria) <3 (severity index)for more than 6 months
• Had not experienced a symptomatic relapse in the 6 months

Exclusion criteria

• Significant abnormality in laboratory tests
• History of head trauma

Trial design

0 participants in 2 patient groups

Controls

Description:

Healthy control

patients

Description:

clinical high risk subjects for psychosis