Antiseptic and Analgesic Action Acmella Oleracea Skin: Randomized Clinical Trial

Ana Beatriz Alkimim Teixeira Loyola

Status: Completed

Conditions: Analgesic; Phythoterapy; Antimicrobial; Venipuncture Site Numbness

Treatments: Other: 70% alcohol; Other: A. oleracea

Study type: Interventional

Funder types: Other

Identifiers

NCT02792972

Carol2014

Details and patient eligibility

About

Context: Research on natural products with therapeutic, analgesic or antimicrobial purpose should be encouraged to create new drugs. Acmella oleracea, typical plant of the Northern region of the country and popularly known as jambu, has aroused the interest of researchers because of its therapeutic potential. Objective: To evaluate the potential topical analgesic and antimicrobial of Acmella oleracea plant extract from the skin antisepsis in venipuncture procedures. Methods: This is a clinical, randomized, controlled trial with healthy volunteers recruited at the Clinic I of the collection of biological materials sector of the Hospital das Clinicas Samuel Libânio, in Pouso Alegre-MG. The plant extract A. oleracea manipulated with Transcutol® and 70% alcohol were used in the volunteers before the venipuncture procedure as allocation in study groups. Held collection of skin microbiota by the swab technique and the end of the venipuncture procedure was applied to the volunteer, the visual numeric scale (VNS) standard to determine the degree of pain.

Full description

Context: Research on natural products with therapeutic, analgesic or antimicrobial purpose should be encouraged to create new drugs. Acmella oleracea, typical plant of the Northern region of the country and popularly known as jambu, has aroused the interest of researchers because of its therapeutic potential. Objective: To evaluate the potential topical analgesic and antimicrobial of Acmella oleracea plant extract from the skin antisepsis in venipuncture procedures. Methods: This is a clinical, randomized, controlled trial with healthy volunteers recruited at the Clinic I of the collection of biological materials sector of the Hospital das Clinicas Samuel Libânio, in Pouso Alegre-MG. The plant extract A. oleracea manipulated with Transcutol® and 70% alcohol were used in the volunteers before the venipuncture procedure as allocation in study groups. Held collection of skin microbiota by the swab technique and the end of the venipuncture procedure was applied to the volunteer, the visual numeric scale (VNS) standard to determine the degree of pain.

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• healthy volunteers
• without restriction as to ethnicity
• educational level and social class who agreed to participate by signing the Informed Consent and Informed (IC )

Exclusion criteria

• pregnant women (due to contractile properties that can cause )
• cancer patients
• chronic and refusal to participate in the study kidney

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups, including a placebo group

Acmella oleracea

Active Comparator group

Description:

The plant extract A. oleracea manipulated with Transcutol® were used in the volunteers 3 minutes before the venipuncture

Treatment:

Other: A. oleracea

alcohol 70%

Placebo Comparator group

Description:

70% alcohol were used in the volunteers 3 minutes before the venipuncture

Treatment:

Other: 70% alcohol