Aortic Balloon Counterpulastion in Myocardial Infarction Related Shock (IABPSHOCK)

Martin-Luther-Universität Halle-Wittenberg

Status: Completed

Conditions: Myocardial Infarction; Cardiogenic Shock

Treatments: Device: Intra-aortic balloon pump counterpulsation

Study type: Interventional

Funder types: Other

Identifiers

NCT00469248

MLU-IABPSHOCK

Details and patient eligibility

About

The role of intra aortic balloon counterpulsation in patients experiencing acute myocardial infarction with shock is not established. We hypothesised that use of such a device would lead to improved outcomes in these patients.

Full description

Patients undergoing percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) with cardiogenic shock (CS) are often treated with Intra-aortic balloon pump counterpulsation (IABP) although the evidence to support this is limited. We conducted a prospective, randomised clinical trial, of IABP as an addition to PCI centred therapy, in patients with AMI complicated by CS.

45 patients with AMI and CS undergoing PCI were randomised to care with or without IABP. Over 4 days, APACHE II scores, haemodynamic parameters, inflammatory markers and BNP levels were collected to assess the impact of IABP treatment on CS triggered multi organ dysfunction syndrome (MODS).

Enrollment: 45 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acute myocardial infarction
• Cardiogenic shock

Exclusion criteria

• Absent peripheral pulses
• Mechanical complications of myocardial infarction

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)