Aortic Elongation and Dissection

Maastricht University Medical Centre (MUMC)

Status: Completed

Conditions: Thoracic Aorta

Study type: Observational

Funder types: Other

Identifiers

NCT02722889

16-4-027

Details and patient eligibility

About

Aim of this study is to measure length of the ascending aorta in adults and to investigate the clinical implication of 'elongation' of the aorta.

Full description

Regarding to aortic geometry, attention is often drawn to aortic diameters since an increase in these diameters (e.g. aneurysm) can lead to life-threatening complications such as dissection and/or rupture. In daily practice however (e.g. imaging reports), the investigators often encounter patients with elongation of the ascending aorta. Little is known about the length of the proximal aorta. Furthermore, the clinical implications of an elongated aorta are unknown.

Enrollment: 298 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Underwent recent (<6 years) contrast-enhanced CT scan which allows for segmentation and assessment of aortic geometry.

Exclusion criteria

• Age <18 years old.
• Prior thoracic, cardiac or aortic surgery.
• Genetic disease with cardiac and/or aortic involvement (e.g. Marfan's disease).
• Infectious disease of the aorta.
• Malignant disease with involvement of heart and/or aorta.

Trial design

298 participants in 2 patient groups

Healthy controls

Description:

Healthy control patients

Type A dissection

Description:

Patients with proven type A dissection,