Apathy in Parkinson Disease: Clinical, Physiopathological and Pharmacological Study

Grenoble Alpes University Hospital Center (CHU)

Status: Unknown

Conditions: Apathy in Parkinson Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01020682

APATHIE

Details and patient eligibility

About

Apathy has been reported to occur after subthalamic nucleus stimulation (STN-DBS), a treatment of motor complications in advanced Parkinson's disease (PD). It is not known whether postoperative apathy is related to dopamine withdrawal or a side effect of STN DBS. The researchers investigated potential predictors of apathy, and the effect of dopamine agonist treatment.

Enrollment: 120 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Parkinson disease

Exclusion criteria

• Mattis scale < 130
• Beck scale > 20