APPEndicitis and Laparoscopic Criteria; APPEL Study

University Medical Center Groningen (UMCG)

Status: Completed

Conditions: Appendicitis

Study type: Observational

Funder types: Other

Identifiers

NCT01054417

APPEL01

Details and patient eligibility

About

A diagnostic laparoscopy is frequently used to confirm the diagnosis of appendicitis. However, laparoscopic criteria for determining appendicitis are not defined. If there is any doubt about the presence of an abnormal appendix, it is usually removed. However, an appendectomy of a negative appendix has a certain morbidity and for that reason it should be avoided. The purpose of this study is to establish laparoscopic criteria for the diagnosis appendicitis during diagnostic laparoscopy.

Full description

The UMCG hospital protocol of suspicion of appendicitis includes a diagnostic laparoscopy. The laparoscopic inspection of the appendix is carried out according to a specific protocol. In case of appendicitis the appendix is removed laparoscopically, a normal appendix is not removed. The primary outcome of the study is: appendicitis according to pathologic examination following appendectomy, or appendicitis according to clinical follow-up in case the appendix is not removed.

The clinical diagnosis of appendicitis in the follow-up should be confirmed radiologic examination (ultrasound, CT-scan, MRI) or by a re-operation.

Enrollment: 142 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Informed consent
• Patients who will undergo a diagnostic laparoscopy for suspicion of appendicitis
• No age or gender limits

Exclusion criteria

• Elective scheduled appendectomy
• Unable to give informed consent

Trial design

142 participants in 1 patient group

Appendicitis

Description:

Patients with suspected appendicitis who are to be operated upon by diagnostic laparoscopy