Appetite Regulation and Mycoprotein (mycoprotein)

Imperial College London

Status: Completed

Conditions: Energy Intake; Appetite

Treatments: Dietary Supplement: control protein; Dietary Supplement: mycoprotein

Study type: Interventional

Funder types: Other

Identifiers

NCT02053025

CRO1332

Details and patient eligibility

About

The purpose of this study is to investigate the effect of eating various levels of mycoprotein (Quorn) on feelings of appetite, energy intake and levels of gut hormones in overweight volunteers.

Full description

Owing to its relatively high protein and fibre content, mycoprotein presents an attractive food product to improve appetite regulation and postprandial glycaemic and insulin responses in overweight and obese individuals at risk of developing T2DM

Enrollment: 52 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Males and females between the ages of 18 and 65
• body mass index (BMI) 25-32kg/m2
• Weight stable over the past 6 months
• No known major illness or eating disorder nor on any medication that may impact on appetite or hormone levels.
• No paracetamol or other analgesic in the previous 48 hours
• A score of <2.5 in the Dutch Eating Behaviour Questionnaire (DEBQ)
• A score of <2 in the SCOFF questionnaire

Exclusion criteria

• Persons outside the age and BMI ranges stated above
• Pregnant and lactating women
• Weight variation of greater than 5% in the last 6 months
• Any diagnosed major illness
• Any paracetamol or analgesic intake in the last 48 hours
• Diagnosed eating disorder
• Allergy to mycoprotein or mushrooms
• Regular consumption of Quorn products
• Dislike of any of the test foods or drinks
• A score of >2.5 in the Dutch Eating Behaviour questionnaire
• A score of 2 or more in the SCOFF questionaire

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

---

52 participants in 2 patient groups

mycoprotein

Active Comparator group

Description:

3 levels of mycoprotein will be consumed

Treatment:

Dietary Supplement: mycoprotein

control protein

Active Comparator group

Description:

3 levels of a control protein will be consumed

Treatment:

Dietary Supplement: control protein