Appetite Response to Exercise- Versus Mixed (Exercise + Dietary Restriction)-Induced Energy Deficit in Adolescents With Obesity (IDEX2)

University Hospital, Clermont-Ferrand

Status: Completed

Conditions: Pediatric Obesity

Treatments: Behavioral: CON . control condition without exercise / rest condition; Behavioral: Def-Mixed. Condition with a mixed energy deficit induced by exercise + dietary restriction.; Behavioral: Def-EI. Condition with an energy-restriction energy deficit

Study type: Interventional

Funder types: Other

Identifiers

NCT04734639

RBHP 2020 JULIAN 2

2020-A03568-31 (Other Identifier)

Details and patient eligibility

About

The aim of the present study is to compare the effect of iso-energetic energy deficits induced by energy restriction alone or exercise + dietary restriction (Mixed deficit) on energy intake and appetite feelings in adolescents with obesity.

Full description

The present study will compare the nutritional response to an energy deficit of 500 kcal induced once by dietary restriction alone and once by a mixed deficit (50% by exercise and 50% by dietary restriction) (compared with a control condition). 18 adolescents with obesity will be asked to randomly complete three experimental sessions: i) one control session (CON); ii) one session with a dietary-induced energy deficit (Def-EI); iii) one session with a mixed deficit (50% by exercise and 50% by dietary restriction) (Def-Mixed).

Their ad libitum energy intake will be assessed at dinner time. Appetite feelings will be assessed at regular intervals and their food reward in response to the lunch will also be assessed.

Enrollment: 17 patients

Sex: All

Ages: 12 to 17 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI percentile > 97th percentile according to the french curves.
• ages 12-16 years old
• Signed consent form
• being registered in the national social security system
• no contraindication to physical activity

Exclusion criteria

• Previous surgical interventions that is considered as non-compatible with the study.
• Diabetes
• weight loss during the last 6 months
• cardiovascular disease or risks

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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17 participants in 1 patient group

Obese adolescents

Experimental group

Description:

20 adolescents with obesity are involved and will perform the three conditions.

Treatment:

Behavioral: Def-EI. Condition with an energy-restriction energy deficit

Behavioral: Def-Mixed. Condition with a mixed energy deficit induced by exercise + dietary restriction.

Behavioral: CON . control condition without exercise / rest condition