Applicability of Uroflowmetry in Children with Cerebral Palsy

Ghent University Hospital (UZ)

Status: Completed

Conditions: Lower Urinary Tract Symptoms; Cerebral Palsy

Treatments: Device: uroflow measurement; Device: Bladder ultrasound

Study type: Interventional

Funder types: Other

Identifiers

NCT05017415

BC-9774

Details and patient eligibility

About

Until now, the use of invasive urodynamics with use of catheters is still the gold standard for lower urinary tract evaluation in subjects with CP. This suggests a psychological and physical impact of invasive urodynamics in subjects with CP and further demonstrates the need to avoid standard use of invasive urodynamics in children and adults with CP.

The current study will evaluate usefulness of uroflowmetry, correlation between uroflowmetry parameters and different lower urinary tract symptoms will be investigated. Secondly, results of uroflowmetry indicating possible vulnerability of the upper urinary tract will be defined.

Full description

A cross-sectional case-control study comparing children with CP and LUTS and children with CP without LUTS will be conducted with the primary objective to investigate correlation between uroflowmetry parameters and different LUTS.

Children will be evaluated with uroflowmetry and subsequent post void residual measurement and the validated vancouver symptom score for dysfunctional elimination syndrome.

Enrollment: 56 patients

Sex: All

Ages: 5 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of cerebral palsy
• Dutch or French speaking child and parent

Exclusion criteria

• History of urological surgery

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

56 participants in 2 patient groups

Standard toilet chair (hip angle 90°)

Experimental group

Description:

uroflow measurement with subsequent post void residual measurement, conducted on a standard toilet chair.

Treatment:

Device: Bladder ultrasound

Device: uroflow measurement

Toilet chair with decreased hip angle

Experimental group

Description:

uroflow measurement with subsequent post void residual measurement, conducted on a toilet chair with decreased hip angle.

Treatment:

Device: Bladder ultrasound

Device: uroflow measurement