Application and Generalization of Flutter Mucus Clearance Device

Tongji University

Status

Completed

Conditions

Pulmonary Disease, Chronic Obstructive

Treatments

Device: flutter mucus clearance device

Study type

Interventional

Funder types

Other

Identifiers

NCT00816881

SHDC12007211

Details and patient eligibility

About

The purpose of this study is to evaluate the clinical outcome and safety of flutter mucus clearance devices.

Full description

Respiratory diseases are still increasing in elder population. Sputum detaining is a common contributing factor to acute exacerbation. The fluttering mucus clearance technique is expected to be a physical assisting therapy enhancing airway secretion clearance but need more clinical randomized control trial evidence.

Enrollment

356 patients

Sex

All

Ages

40 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Pulmonary department: available to perform the device, in-hospital patients
- Male and female
- Age: 45 - 85 years
- Chronic bronchitis, COPD
Thoracic surgery department and surgical department (upper abdomen):
- Patients with endotracheal intubation of general anesthesia
- Age: 40-75 years

Exclusion criteria

Not available to perform the procedure
Untreated pneumothorax
Diffusion interstitial lung disease
Acute coronary syndrome
Third stage hypertension
Advanced cancer
Severe heart, liver, renal , blood system and endocrine system dysfunction
Noninvasive mechanical ventilation more than 6 hrs per day
Patients with invasive ventilation and cannot weaning and extubation within 48 hours
Active hemoptysis