Application of Auricular Point Sticking in Patients With Taste Alteration

Affiliated Hospital of Jiangnan University

Status: Completed

Conditions: Chemotherapy Effect; Acupressure; Dysgeusia

Treatments: Behavioral: auricular point sticking

Study type: Interventional

Funder types: Other

Identifiers

NCT05868850

1415322141

Details and patient eligibility

About

To explore the intervention effect of auricular point sticking on chemotherapy-induced taste alterations in cancer patients, and analyze its relationship with quality of life, nutritional status and psychology of patients.

Full description

Taste alteration is a common adverse reaction in patients with chemotherapy. The incidence of taste alteration varies with chemotherapy drugs, ranging from 36% to 84%, among which platinum chemotherapeutic drugs are most likely to cause severe taste alteration. The taste alteration does not pose a serious threat to the life of patients, so it is often ignored by patients and medical staff. Dysgeusia is positively correlated with the loss of appetite, which can directly lead to the loss of appetite and insufficient intake of nutrients in patients, and even stimulate patients' anxiety, psychological pain and other negative emotions. In severe cases, it can cause malnutrition, reduce the chemotherapy compliance of cancer patients, and ultimately reduce the quality of life of patients. Therefore, for patients with platinum chemotherapy, it is necessary to pay close attention to the change of taste during chemotherapy, and apply effective nursing interventions to pay attention as soon as possible, so as to improve the quality of life of patients.

Enrollment: 120 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients with malignant tumors diagnosed by histopathology or pathology;
2. Age ≥18 years old;
3. Patients who received platinum-based chemotherapy and completed at least one cycle of chemotherapy;
4. According to the chemotherapy-induced taste Changes Scale (CiTAS), the score of patients was ≥6;
5. Patients voluntarily participated in the treatment with good compliance and adherence.

Exclusion criteria

1. Patients with treatment plan adjustment or concurrent radiotherapy;
2. Patients with abnormal taste and malnutrition caused by various reasons before chemotherapy;
3. Patients with inflammation of the external ear or eczema, ulcers, chilblain in the pressing area;
4. Allergic or intolerant to adhesive stickers;
5. Those who were lost to follow-up or withdrew voluntarily;
6. Patients enrolled in other studies at the same time.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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120 participants in 2 patient groups

Routine care group

No Intervention group

Description:

The control group receives routine nursing, including admission education, routine nursing of adverse reactions to chemotherapy, diet guidance for chemotherapy patients, precautions for various examinations, discharge guidance and follow-up.

Auricular point sticking group

Experimental group

Description:

Auricular point sticking therapy is performed on the basis of control group. The acupoint intervention group is established, and the research team consists of 2 graduate students, 1 graduate supervisor, 1 head nurse, 1 chief physician of traditional Chinese medicine, and 1 nursing expert. The nursing expert is responsible for the overall design of the project, and the director of traditional Chinese medicine is responsible for the selection of acupoints and the training of nurses for massage. The supervisor of graduate students and the head nurse are responsible for the overall quality control of the intervention process, while the graduate students are responsible for the preliminary and final screening of research objects, the implementation of intervention programs, the organization, coordination and recording of the entire intervention process and the collection of data.

Treatment:

Behavioral: auricular point sticking