Application of Combined Lumbar Plexus and Sciatic Nerve Block

Guangzhou General Hospital of Guangzhou Military Command

Status and phase: Completed; Phase 4

Conditions: Anesthesia

Treatments: Drug: Bupivacaine; Drug: Ropivacaine; Procedure: Combined spinal and epidural anesthesia; Procedure: Nerve block

Study type: Interventional

Funder types: Other

Identifiers

NCT02084368

Nerve Block

Details and patient eligibility

About

The research is to study the effectiveness and safety of combined lumbar plexus and sciatic nerve block by the guide of peripheral nerve stimulator (PNS) in unilateral knee replacement.There have be some papers which supported that combined lumbar plexus and sciatic nerve block may be more suitable for the old men.

Enrollment: 34 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients of American Association of anesthetists（ASA）Grade 1、2 or 3
2. Aged between 18 and 85 years
3. Undergoing elective total knee replacement.

Exclusion criteria

1. Mental illness can not match
2. Nerve block, epidural anesthesia contraindicated
3. People who have Slow-type arrhythmias
4. History of chronic headaches and long-term use of analgesic drugs
5. People who were postoperative consciousness, language or hearing impaired

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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34 participants in 2 patient groups, including a placebo group

Nerve block

Experimental group

Description:

Patients in this group were assigned to receive lumbar plexus block and sciatic nerve block guided by PNS.

Treatment:

Drug: Ropivacaine

Procedure: Nerve block

combined spinal and epidural anesthesia

Placebo Comparator group

Description:

Combined spinal and epidural anesthesia were performed in patients of this group.

Treatment:

Procedure: Combined spinal and epidural anesthesia

Drug: Bupivacaine