Application of Indicator Based-electrical Impedance Tomography Method Assess Lung Regional Perfusion in ICU Patients

Yun Long

Status: Completed

Conditions: Respiratory Failure; ARDS, Human; Hypoxemia

Study type: Observational

Funder types: Other

Identifiers

NCT04081142

EIT-lung Perfusion in ICU

Details and patient eligibility

About

This study is an observational study. Investigate the relationship of oxgenation and lung regional ventilation and perfusion assessed by the indicator based-EIT method in the critically ill patients in ICU

Full description

1. Written informed consent was obtained from all patients or next of kin before data were included in the study.
2. When the research team was available, adult patients within 1w, who were sequentially admitted to the Department of Critical Care Medicine and required central venous catheters for resuscitation were eligible for the study.
3. Information collected at enrollment included demographic characteristics such as age, sex, Acute Physiology and Chronic Health Evaluation II score (APCHEII); . The global hemodynamic, respiration condition and PaO2 were measured. At the same time, the lung regional ventilation and perfusion assessed by the indicator based-EIT method(injection 10%NaCL).
4. The 10%NaCL was injected by the central venous catheter.

Enrollment: 119 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Time of admission ICU < 7days
• Age (> 18 years old)
• Have been placed central venous catheter based on clinical requirement

Exclusion criteria

.Chest skin injured and cannot be monitored by EIT.

• Severe Hypernatremia
• Pregnancy

Trial design

119 participants in 2 patient groups

acute respiratory failure group

Description:

acute respiratory failure (ARF) group: arterial oxygen partial pressure to fractional inspired oxygen ratio, PaO2/FiO2\<300 mmHg and/or peripheral oxygen saturation SaO2\<94% under air condition and/or severe dyspnea with respiratory rate \>30bpm.

control group

Description:

postoperative ICU patients without ARF were included