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Application of Ultra-high Frequency Ultrasonography (UHFUS) to the Study of Gingival Tissues

U

University of Pisa

Status

Enrolling

Conditions

Periodontitis
Gingivitis

Treatments

Other: Performance of ultrasonographic scan

Study type

Observational

Funder types

Other

Identifiers

NCT06480825
7935870439

Details and patient eligibility

About

Gingival inflammation triggered by the accumulation of bacterial is the primary risk factor for the development of periodontitis. Clinically, localized signs of inflammation limited to the gingiva, presence of significant bacterial plaque load, and stable attachment levels on the periodontium can be observed in course of gingivitis. The aim of the present study is to compare clinical aspects of gingival tissue in healthy patients versus patients with gingivitis to assess the ultrastructural variations present in course of inflammation.

Patients with gingivitis and healthy controls will be enrolled. All patients will undergo ultra-high frequency ultrasonographic scans (70 MHz) of gingival tissue on three areas per dental arch (anterior, middle right, middle left). Gingival thickness, echogenicity, and vascularization assessed through resisitive index will be evaluated.

Enrollment

40 estimated patients

Sex

All

Ages

18 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • males or females of age > 18 years
  • presence of at least 20 teeth
  • full-mouth plaque score (FMPS) >50%
  • FMBS >30%
  • ability and willingness to give informed consent

Exclusion criteria

  • pregnancy or breastfeeding
  • pharmacological treatment with antinflammatory drugs, statins, or either local or systemic antibiotics (within the previous 30 days)
  • smoking habit
  • dental or periodontal condition requiring immediate treatment
  • refusal to be enrolled in the study

Trial design

40 participants in 2 patient groups

Gingivitis group
Description:
patients affected by gingivitis
Treatment:
Other: Performance of ultrasonographic scan
Control group
Description:
Periodontally healthy patients
Treatment:
Other: Performance of ultrasonographic scan

Trial contacts and locations

2

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Central trial contact

Rossana Izzetti

Data sourced from clinicaltrials.gov

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