Applying High Resolution Impedance Manometry for Perioperative Swallowing Changes in Older Patients Receiving Endotracheal Intubation or Supraglottic Airway Devices During Orthopedic Surgery

National Taiwan University

Status: Completed

Conditions: Hypopharyngeal Mean Pressure

Treatments: Device: endotracheal intubation; Device: supraglottic airway device

Study type: Interventional

Funder types: Other

Identifiers

NCT05420428

202204071RINC

Details and patient eligibility

About

We aimed to investigate whether patients with tracheal intubation has high hypopharyngeal pressure than patients with supraglottic airway does by using high resolution impedance manometry. We expected that the patients with endotracheal intubation have higher hypopharyngeal pressure than the patients with supraglottic airway devices.

Full description

Background: More and more older patients required to receive orthopedic surgery recently. The intubation or supraglottic airway device are required to maintain airway during general anesthesia. Previous studies only reported the subjective swallowing discomfort feeling, however, the objective data was limited. The high-resolution impedance manometry could detect the swallowing muscle power changes with multiple pressure sensors and impedance channels.

Objectives: we aimed to investigate whether patients with tracheal intubation has high hypopharyngeal pressure than patients with supraglottic airway does Patients and methods: The patients receive orthopedic surgery with older than 60 years old. They received high resolution impedance manometry examination at preoperative day, in the post-anesthetic care unit, postoperative day 3 to 7 (pick a day) along with subjective questionnaires. We also followed the IDDSI guideline to test different viscosity of the patients' tolerance for food.

Expected result: The patients with endotracheal intubation have higher hypopharyngeal pressure than the patients with supraglottic airway devices.

Enrollment: 32 patients

Sex: All

Ages: 60 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The patients receive orthopedic surgery with older than 60 years old including 60 years old.

Exclusion criteria

• The patients had severe major organ dysfunction

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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32 participants in 2 patient groups, including a placebo group

endotracheal intubation

Placebo Comparator group

Description:

under general anesthesia, patients received tracheal intubation.

Treatment:

Device: endotracheal intubation

supraglottic airway device

Experimental group

Description:

under general anesthesia, patients received supraglottic airway device

Treatment:

Device: supraglottic airway device