Aquagenic Wrinkling Prediction

University of Iowa

Status: Enrolling

Conditions: Carrier State; Aquagenic Wrinkling of Palms

Treatments: Procedure: Aquagenic Wrinkling

Study type: Observational

Funder types: Other

Identifiers

NCT06831110

202410028

Details and patient eligibility

About

The goal of this observational study is to determine whether an aquagenic wrinkling procedure (i.e., soaking hands in a water bath for up to 20 minutes) can be used as a screening tool for cystic fibrosis carrier status.

Participants will complete one visit where they will undergo an aquagenic wrinkling procedure to see how their hands respond.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 18 to 24 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Interested in participating in other CF Carrier-related research studies.

Exclusion criteria

• CF patient status
• Unable to speak English
• Unable to provide written informed consent
• Prisoner status
• An open wound on either hand
• A tattoo on either hand
• Missing any portion of either hand
• Diagnosis of Diabetes
• Diagnosis of Hyperhidrosis
• Diagnosis of Raynaud's Disease
• Diagnosis of Atopic Dermatitis
• Regularly taking ACE inhibitors or angiotensin receptor blockers

Trial design

2,000 participants in 2 patient groups

Potential Cystic Fibrosis Carriers

Description:

Participants that are identified as potential cystic fibrosis carriers based on aquagenic wrinkling results.

Treatment:

Procedure: Aquagenic Wrinkling

Potential Controls

Description:

Participants that are identified as potential controls based on aquagenic wrinkling results.

Treatment:

Procedure: Aquagenic Wrinkling