Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD

Ankara University

Status: Completed

Conditions: Acute Exacerbation of COPD; Chronic Obstructive Lung Disease; Comorbidities and Coexisting Conditions

Treatments: Other: Frequency of AECOPD

Study type: Observational

Funder types: Other

Identifiers

NCT05504993

05-305-18

Details and patient eligibility

About

INTRODUCTION: Relationship between comorbidities and COPD is two-sided. While the number of comorbidities increasing, the frequency of acute exacerbations of COPD (AECOPD) is increasing, too. Comorbidity indexes can be used for recognition of comorbidities while managing COPD patients. In the present study, it is aimed to compare comorbidity indexes such as Charlson Comorbidity Index, COMCOLD and COTE in the matter of exacerbation frequency.

METHOD: Subjects hospitalized for AECOPD, admitted to the study. Exacerbation severity, frequency, further exacerbations for a 1-year period in the follow-up period and CCI, COMCOLD and COTE scores were recorded. High and low comorbidity groups were compared for AECOPD frequency, severity, and further exacerbations.

Enrollment: 92 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• COPD patients
• Admitted to the ward for AECOPD

Exclusion criteria

• Not giving informed consent
• Unable to perform PFT
• Lost to follow-up

Trial design

92 participants in 2 patient groups

High comorbidity group

Description:

CCI equal or higher than 2 COTE equal or higher than 4 COMCOLD equal or higher than 4

Treatment:

Other: Frequency of AECOPD

Low comorbidity group

Description:

CCI lower than 2 COTE lower than 4 COMCOLD lower than 4

Treatment:

Other: Frequency of AECOPD