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Are Sutures Required for Vaginal Hysterectomy: A Randomized Controlled Trial (HAVE)

S

Southern Health

Status and phase

Unknown
Phase 1

Conditions

Vaginal Hysterectomy

Treatments

Procedure: Performing Vaginal hysterectomy with Harmonic Scalpel

Study type

Interventional

Funder types

Other
Industry

Identifiers

NCT00456170
Harmonic Vag Hyst

Details and patient eligibility

About

The hypotheses of this study is that the use of the instrument "Harmonic Scalpel" (ultrasonic shears) for vaginal hysterectomy instead of traditional sutures confers advantage over the use of traditional clamps and sutures. The proposed benefits and outcome measures are reduced blood loss, reduced operating time, reduced post-operative pain and earlier discharge from hospital. Other outcome measure will include complications and cost.

Full description

Patients booked for vaginal hysterectomy at Southern Health will be offered participation in this trial, and randomised to two separate groups: procedure using ultrasonic shears or traditional sutures. Each patient will receive detailed explanation in document form as well as from the Gynaecology registrar in pre-admission clinic prior to obtaining consent.

After the procedure of vaginal hysterectomy, a research associate will follow these patients up until discharge, collecting relevant data.

A statistician has been employed to perform power calculations, and to analyse data after collection, looking at outcomes mentioned above.

The Harmonic Scalpel has been extensively used to replace the use of traditional clamping and suturing in General Surgery, Laparoscopic surgery, and specifically Total Laparoscopic Vaginal Hysterectomies, but it has never been subjected to a randomised control trial to confirm the anecdotal benefits of the device.

Sex

Female

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Any patient already on waitlist requiring vaginal hysterectomy

Exclusion criteria

  • No patient consent

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

Trial contacts and locations

1

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Central trial contact

Jason J Tan, MBBS, MRANZCG; Geoff Edwards, MBBS> FRANGCOG

Data sourced from clinicaltrials.gov

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