Arm Motor Control on Bi and Uni ADLs (BiAs)

University of Pennsylvania

Status: Terminated

Conditions: Peripheral Neuropathy; Spinal Cord Injuries; Stroke; Cerebral Palsy

Treatments: Device: Bilateral assessment robots (BiAS)

Study type: Interventional

Funder types: Other

Identifiers

NCT02778529

820251

Details and patient eligibility

About

This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs. By studying the kinematics of the respective cohort of study participants as they are assessed performing common activities of daily living (ADLS), the investigators research team aims to better understand how impaired neural pathways, and pathways that have been impaired at various points along the pathway, deleteriously affect ADLs in patients with differing long-term disabilities.

Full description

Cross-sectional study comparing bilateral ADL activities for stroke survivors, SCI paraplegics, UE amputees, adults with CP, and healthy controls. The study participants will perform 4 ADL tasks with the BiAS passive robots. From these tasks, the BiAS robots will provide information regarding position, velocity, distance, displacement, etc. This, along with video information provided by the 3D Kinect and EEG neuroheadset, will be used as the basis of the investigators data and aid in informing members of the research team on how the respective impairments affected upper limb kinematics on ADL tasks.

Participation in the study will include the following steps:

1. Informed Consent: After arrival, subjects will review and sign the consent form with study personnel present.
2. Pre-Assessments: A member of the research team will evaluate the subjects' upper extremity and assess their ability to use it. Subjects will be evaluated using a battery of assessments such as, but not limited to, the Box and Block, Pin and Prick, and grip strength using a dynamometer.
3. Break: Subjects will be given a 15 minute break.
4. BiAS passive robot system: Subjects will be introduced to the device and each wrist will be placed on to the end of each robot. As common therapy tasks are performed by the subject, the BiAS devices will collect the data along with the video from 3D Kinect, ECG gelled electrodes, and the EEG neuroheadset. After each of the 4 ADL activities, subjects will be asked about their level of exercise and discomfort, if any. After subjects finish all exercises with the BiAS, they will be thanked for their participation in the study.
5. Video and photos may be collected to determine subject quality of ADL movement.

Enrollment: 18 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Study will include subjects 18 years of age or older from any of the below groups:

• Stroke survivors, 3 months post event
• Upper extremity amputees, 3 months post event
• Cervical SCI (C-5 to C-7), 3 months post event
• Cerebral palsy participants
• Healthy participants

Exclusion criteria

• The inability to perform at least some aspects of ADL tasks such as drinking, pouring, pinching, and grasping.
• Severe spasticity

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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18 participants in 1 patient group

Upper Limb Assessment on ADLs

Other group

Description:

Bilateral assessment robots (BiAS) Evaluate upper limb kinematics of Stroke, Amputees, SCI, Cerebral Palsy and Health Subjects will be assessed as they complete unilateral and bilateral activities of daily living. Subjects will complete exercises in 1 session

Treatment:

Device: Bilateral assessment robots (BiAS)