Aronia, Cognition, and Eye Health (ACE)

Maastricht University Medical Centre (MUMC)

Status: Enrolling

Conditions: Cognitive Function

Treatments: Dietary Supplement: Aronia supplementation; Dietary Supplement: Cellulose supplementation

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT05683002

BB-04

Details and patient eligibility

About

There is great interest in improving cognitive performance and eye health as working from home becomes more prominent. Working from home as well as stress in the workplace is an increasing problem. Students and work professional can therefore benefit from improved attention and thus performance in academic and other work environments. A completely natural supplement with aronia melanocarpa extract could be a promising way to naturally improve cognitive performance

Full description

The shift of on-site education/working to online education/working has had a detrimental impact on motivation to study or work and ultimately on mental health. Moreover, online education has been shown to have a negative effect on concentration, learning, and academic performance. Stress in the workplace is an increasing problem, leading to decreased productivity and overall well-being of working adults. Consequently, there is a great interest in improving cognitive performance, including memory and attention.

Previous studies in young adults have mainly focused on acute or short-term (e.g. 1 week) effects of anthocyanin supplementation on cognitive performance. The research hypothesis of the current study is that long term (6 weeks) AME supplementation affects domains of cognitive performance in a randomized, double-blind, placebo controlled, cross-over study in healthy young adults (18-35 years old).

Enrollment: 44 estimated patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy men and women, aged between 18-35 years
• BMI between 18-30 kg/m2
• Systolic blood pressure < 160 mmHg and diastolic blood pressure < 100 mmHg
• Stable body weight (weight gain or loss < 3 kg in the past three months)
• Willingness to give up being a blood donor from 8 weeks before the start of the study, during the study and for 4 weeks after completion of the study
• No difficult venipuncture as evidenced during the screening visit

Exclusion criteria

• Smoking or smoking cessation < 12 months
• Contact lens wearers
• Past refractive surgery
• Severe medical conditions, including asthma, chronic obstructive pulmonary disease (COPD), kidney failure, auto-inflammatory diseases, rheumatoid arthritis, diabetes mellitus, cardiovascular disease
• Use of dietary supplements or medication affecting the main outcomes of the study
• Use of an investigational product within another biomedical intervention trial within the previous month
• Familial hypercholesterolemia
• Abuse of drugs
• More than 3 alcoholic consumptions per day

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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44 participants in 2 patient groups, including a placebo group

Aronia

Experimental group

Description:

Aronia Melanocarpa supplementation

Treatment:

Dietary Supplement: Aronia supplementation

Control

Placebo Comparator group

Description:

Cellulose supplementation

Treatment:

Dietary Supplement: Cellulose supplementation