Arrhythmia in on Pump vs. Off Pump Coronary Artery Bypass Grafting

Assiut University

Status: Unknown

Conditions: Ischemic Heart Disease

Treatments: Device: cardio pulmonary bypass machine

Study type: Observational

Funder types: Other

Identifiers

NCT04093817

Arrhythmia in CABG

Details and patient eligibility

About

The aim of this research is to know the incidence of arrhythmias in on vs. off pump CABG and to know their relations to the patient's morbidity and mortality, hospital stay and hospital costs.

Full description

On pump vs. off pump CABG has been a topic of debate for many years regarding the benefits and the risks of each technique .Off pump CABG began 30 years ago. Its promotion was based on its potential benefits over some of the limitation of traditional on pump CABG. It avoids the trauma of cardiopulmonary bypass (CPB) and minimizing aortic manipulation and reducing length of hospital stay and morbidity.

There is a criticism regarding completence of revascularization in off pump vs. on pump CABG, this is no longer valid in the current era as technology to safely perform multi vessel off pump has improved tremendously over the past decade.

One of the debates between these two techniques was the incidence of arrhythmias in and after the operation and its relation to morbidity and mortality at the operation and hospital stay after the operation.

As known atrial fibrillation (AF) is still the most common arrhythmia that occur after CABG and although in some studies it has been considered a benign and self-limiting complication, some suggest serious morbidity and mortality from this complication, it is said that it affects more than 40% of patients underwent CABG. Atrial fibrillation (AF) may lead to thromboembolic complications, additional pharmacotherapy, longer hospital stay, increase cost, anxiety and stroke.

Most AF post CABG are found in the second to third post-operative day. SO, on this study the investigators focus one the incidence of arrhythmias, especially AF in those two techniques and their relations to patients' morbidity and mortality.

Enrollment: 50 estimated patients

Sex: All

Ages: 40 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients subjected to CABG

Exclusion criteria

• Associated valvular heart disease
• Emergency cases
• Previous AF

Trial design

50 participants in 2 patient groups

on pump CABG

Description:

patients under going CABG with cardiopulmonary bypass machine

Treatment:

Device: cardio pulmonary bypass machine

off pump CABG

Description:

patients under going CABG without cardiopulmonary bypass machine