Arterial Stiffness in Chronic Kidney Disease

University of Edinburgh

Status: Completed

Conditions: Chronic Kidney Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01770847

12\SS\0088

Details and patient eligibility

About

Diurnal variations in the cardiovascular system apparent in healthy individuals, are different in chronic kidney disease patients. Therefore, diurnal variations in arterial stiffness may also differ in chronic kidney disease patients. This study aims to identify and evaluate diurnal variations in arterial stiffness in chronic kidney disease patients and compare them to those in age matched healthy controls.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 79 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Systolic blood pressure <160 whether or not on antihypertensive medication
• diastolic blood pressure <100mmHg whether or not on antihypertensive medication
• Chronic kidney disease stage 2-5

Exclusion criteria

• Systolic blood pressure ≥160mmHg
• Diastolic blood pressure ≥100mmhg
• Significant comorbidity (investigator opinion but to include alcoholism and terminal illness)

Trial design

50 participants in 2 patient groups

Healthy controls

Description:

Healthy age matched controls

Chronic kidney diease

Description:

Chronic kidney disease patients stage 2-4