Arterial Waveform Analysis Applying Different Positive End-Expiratory Pressure (PEEP) Levels in Healthy Volunteers

University of Pisa

Status: Completed

Conditions: Blood Pressure

Treatments: Other: progressive increasing of PEEP level.

Study type: Interventional

Funder types: Other

Identifiers

NCT03294928

UPisa - 2017

Details and patient eligibility

About

Population in study will be selected from students and staff of the University of Pisa. Right carotid artery contour wave analysis will be performed during the application of different PEEP levels (from 0 cmH2O to 10 cmH2O) with applanation tonometry technique.

Enrollment: 62 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age between 18 and 40, absence of any chronic diseases, no smoke, no drugs assumptions, no use of caffeine the day of the exam

Exclusion criteria

• pregnancy, chronic diseases, smokers, and intake of caffeine the day of the exam.

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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62 participants in 1 patient group

progressive increasing of PEEP level

Experimental group

Description:

four-step measurements of central artery blood pressure evaluating contour wave analysis during a progressive increasing of PEEP level.

Treatment:

Other: progressive increasing of PEEP level.