Arthrocentesis Alone Versus Arthrocentesis With Hyaluronic Acid Injection

Assiut University

Status: Not yet enrolling

Conditions: Arthrocenteses; Temporomandibular Joint Dysfunction Syndrome; Hyaluronic Acid

Treatments: Procedure: arthrocentesis with hyaluronic acid injection; Procedure: arthrocentesis alone

Study type: Interventional

Funder types: Other

Identifiers

NCT05962619

AHAI

Details and patient eligibility

About

Comparison between Arthrocentesis alone arthrocentesis with hyaluronic acid injection in management of temporomandibular joint dysfunction in the form of anterior disc displacement with reduction.

Full description

Temporomandibular joint (TMJ) anterior disc displacement (ADD) is one of the most common TMJ disorders.It can occur in all age groups, with a high prevalence in adolescents .

ADD often presents with clicking, joint pain, a limited range of mouth opening. Furthermore,ADD might lead to osteoarthrosis .

Since ADD of the TMJ can lead to various harmful outcomes, how to manage ADD is considered a key problem for most TMJ experts. It has been difficult for most clinicians to select a suitable method for ADD patients with different grades of severitis ). Initially, these conditions can be managed conservatively by employing techniques such as occlusal splint therapy, physiotherapy, pharmacotherapy and occlusal treatments. If Medical treatment fails, minimally invasive (sodium hyaluronate or corticosteroid infiltrations and arthrocentesis) and invasive treatments (arthroscopy, arthroplasty, arthrotomy, discectomy, condylotomy) are formed ). Sodium hyaluronate is a buffered solution of hyaluronate acid sodium salt, which is an essential component of the cartilage.It acts against the disintegration of the extracellular matrix.It reduces friction, and it features an anti-inflamatory effect. It is indicated for the treatment of osteoarthritic symptoms and inflammatory degenerative joint disease). Intra-articular hyaluronic acid injection provides long-term palliative effects on symptoms and signs of TMJ pain .

Enrollment: 42 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults with age between( 18-45) years
• Both genders
• The cases ciinically have either of ( limitation of mouth opening , pre-auricular pain , headache, temporal, and occipital tenderness ) and radiologically (MRI) diagnosed as ADD with reduction
• The patients have symptom durations for more than 3 months with medical treatment.
• Patients whom did not respond to medical treatment

Exclusion criteria

• Previous TMJ surgery or previous arthrocentesis.
• Patients with arthritis or history of condylar trauma
• Patients with degenerative change of the condylar head and with facial asymmetry, retrognathism, or prognathism
• Severe co-morbid conditions (uncontrolled diabetes, Hypertenion

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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42 participants in 2 patient groups

Arthrocentesis alone

Experimental group

Description:

Arthrocentesis alone in management of temporomandibular joint dysfunction in the form of anterior disc displacement with reduction.by lavage by normal saline and during the lavage the mandible is moved through opening, excursive, and protrusive movements to facilitate lysis of adhesions.

Treatment:

Procedure: arthrocentesis alone

arthrocentesis with hyaluronic acid injection

Experimental group

Description:

arthrocentesis with hyaluronic acid injection in management of temporomandibular joint dysfunction in the form of anterior disc displacement with reduction. after arthrocentesis is completed, lavage is done by hyaluronic acid injection

Treatment:

Procedure: arthrocentesis with hyaluronic acid injection