Arthroscopic Rotator Cuff Repair With Platelet-Rich Plasma(PRP) in Large to Massive Tears

Seoul National University

Status: Completed

Conditions: Rotator Cuff Tear

Treatments: Procedure: Conventional arthroscopic rotator cuff repair; Procedure: Arthroscopic rotator cuff repair with PRP

Study type: Interventional

Funder types: Other

Identifiers

NCT01238302

BRM-10-03

Details and patient eligibility

About

• The purpose of this study is to compare the clinical and anatomical outcomes of rotator cuff repair with Platelet-Rich Plasma(PRP) and conventional rotator cuff repair in treatment of large to massive rotator cuff tears.
• PRP application to arthroscopic rotator cuff repair would accelerate recovery after arthroscopic rotator cuff repair in terms of pain relief, functional outcomes, overall satisfaction, and enhance structural integrity of repaired tendon.

Enrollment: 48 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

large to massive rotator cuff tear as a determined by clinical examination and MR prior to surgery.

Exclusion criteria

• previous history of shoulder surgery
• acute trauma
• chronic dislocation
• pyogenic infection
• rotator cuff arthropathy with glenohumeral osteoarthritis and superior migration of the humeral head
• showed abnormal serological test results
• thrombocytopenia (platelets less than 15000 per microliter)
• had been received anti-platelet medication
• psychiatric problems that precludes informed consent or inability to read or write
• other serious problems that preclude participation of the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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48 participants in 2 patient groups, including a placebo group

Conventional group

Placebo Comparator group

Treatment:

Procedure: Conventional arthroscopic rotator cuff repair

PRP group

Experimental group

Treatment:

Procedure: Arthroscopic rotator cuff repair with PRP