Articaine 4% Versus Lidocaine 2% for Local Anesthesia of MIH-affected Maxillary Molars

Tishreen University

Status and phase: Completed; Phase 2; Phase 1

Conditions: Molar Incisor Hypomineralisation

Treatments: Drug: Articaine 4%; Drug: Lidocaine 2%

Study type: Interventional

Funder types: Other

Identifiers

NCT05585112

Tishreen U _Local anesthesia

Details and patient eligibility

About

Comparison of injection pain with lidocaine and articaine. Comparison of the efficacy of lidocaine and articaine during treatment of MIH- maxillary molars.

Design: A randomized, controlled, crossover, Triple-blinding clinical study including twenty six cooperative children, aged 6-12years old

Full description

Background and Aims: Some dentists have difficulty obtaining effective anesthesia when treating MIH molars.

There are no studies comparing the effectiveness of lidocaine and articaine in MIH-maxillary molars.

Design: A randomized, controlled, crossover, Triple-blinding clinical study including twenty six cooperative children , aged 6-12 years old. Each child was randomly assigned to either articaine 4% or lidocaine 2% in their first session with the second solution being used at the second session.

Enrollment: 26 patients

Sex: All

Ages: 6 to 12 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Absolute positive or positive behavior according to the Frankel Scale.
• child is not under the effect of any analgesics or sedatives and their weight was more than 20 kg.
• Healthy, both physically and mentally
• A child with a MIH-affected maxillary permanent first molar on the right and left sides .

Exclusion criteria

• children who are uncooperative
• allergic anesthetics used in the study
• children who show inflammation in the injection site.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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26 participants in 2 patient groups

A (Lidocaine 2%)

Active Comparator group

Description:

26 children will be injected with 1 ml of lidocaine 2% with epinephrine

Treatment:

Drug: Lidocaine 2%

B (Articaine 4%)

Experimental group

Description:

26 children will be injected with 1 ml of Articaine 4% with epinephrine.

Treatment:

Drug: Articaine 4%