Artificial Intelligence in Assessing Gastric Intestinal Metaplasia Via the EGGIM Score

Shandong University

Status: Enrolling

Conditions: Artificial Intelligence; Endoscopy; Intestinal Metaplasia of Gastric Mucosa

Treatments: Diagnostic Test: The diagnostic performance of AI system and endoscopists

Study type: Observational

Funder types: Other

Identifiers

NCT07257796

2025SDU-QILU-5

Details and patient eligibility

About

The endoscopic grading system (EGGIM) has been widely used to assess the extent of gastric intestinal metaplasia during endoscopy. Investigators developed an artificial intelligence (AI) system to automatically evaluate the extent of gastric intestinal metaplasia (GIM) and calculate the EGGIM scores in endoscopy examination. This study is a prospective, multi-center study aimed at exploring the performance and reliability of AI-EGGIM scoring.

This is a prospective study designed to validate the AI-EGGIM system in a larger cohort. The study protocol was developed based on preliminary experience from a prior investigation (NCT05464108).

Full description

Gastric intestinal metaplasia (GIM) is an important precancerous stage in the gastric carcinogenesis cascade. The endoscopic grading system (EGGIM) has been proposed as a practical method to evaluate the extent of GIM during endoscopy. Investigators developed an artificial intelligence (AI) system to automatically assess the extent of GIM and calculate EGGIM scores from endoscopic examinations. This study is a prospective, multi-center study aimed at evaluating the accuracy, performance, and reliability of AI-assisted EGGIM scoring.

Enrollment: 3,000 estimated patients

Sex: All

Ages: 40 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients aged 40-75 years who undergo the IEE examination
• patients who voluntarily sign the informed consent form

Exclusion criteria

• patients with severe cardiac, cerebral, pulmonary or renal dysfunction or psychiatric disorders who cannot participate in gastroscopy
• patients with previous surgical procedures on the stomach