AS-OCT Guided Treatment of Diffuse CSCC

Benha University

Status: Completed

Conditions: Conjunctival Neoplasms

Treatments: Procedure: Treatment of diffuse ocular surface squamous neoplasia

Study type: Observational

Funder types: Other

Identifiers

NCT03515954

benha19992

Details and patient eligibility

About

A prospective study was performed on 8 eyes of 8 patients who underwent amniotic membrane graft after diffuse conjunctival squamous cell neoplasia excision followed by topical mitomycin C 0.04% eye drop between March 2014 and January 2018.

Full description

Surgical excision of the conjunctival tumour . A superficial corneal scraping was performed for corneal lesion then double freeze-thaw cryotherapy was applied to limbal edge and conjunctival margins.The amniotic membrane graft was secure and attached to the sclera and conjunctiva using fibrin glue.Topical mitomycin C 0.04%eye drop was prescribed 4 times daily per treatment cycle (1 cycle=1 week on 1 week off).

Enrollment: 15 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diffuse Ocular Surface Squamous Neoplasia

Exclusion criteria

• localized OSSN (less than five clock hours in limbal extent)