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AS-OCT Guided Treatment of Diffuse CSCC

B

Benha University

Status

Completed

Conditions

Conjunctival Neoplasms

Treatments

Procedure: Treatment of diffuse ocular surface squamous neoplasia

Study type

Observational

Funder types

Other

Identifiers

NCT03515954
benha19992

Details and patient eligibility

About

A prospective study was performed on 8 eyes of 8 patients who underwent amniotic membrane graft after diffuse conjunctival squamous cell neoplasia excision followed by topical mitomycin C 0.04% eye drop between March 2014 and January 2018.

Full description

Surgical excision of the conjunctival tumour . A superficial corneal scraping was performed for corneal lesion then double freeze-thaw cryotherapy was applied to limbal edge and conjunctival margins.The amniotic membrane graft was secure and attached to the sclera and conjunctiva using fibrin glue.Topical mitomycin C 0.04%eye drop was prescribed 4 times daily per treatment cycle (1 cycle=1 week on 1 week off).

Enrollment

15 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • diffuse Ocular Surface Squamous Neoplasia

Exclusion criteria

  • localized OSSN (less than five clock hours in limbal extent)

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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