AS-OCT of the Cornea in Thyroid Diseases

Minia University

Status

Unknown

Conditions

Thyroid Eye Disease

Treatments

Diagnostic Test: AS-OCT

Study type

Observational

Funder types

Other

Identifiers

NCT05241626

165-2021

Details and patient eligibility

About

use the anterior segment optical coherence tomography (AS-OCT) to evaluate the tear meniscus parameters, total corneal thickness (CT), and epithelial thickness in active and inactive thyroid eye diseases (TED) patients and compare them with age-matched controls.

Full description

A prospective case-control clinical study. The study subjects were divided into 3 groups, group 1 of inactive thyroid patients, group 2 of active thyroid patients, and group 3 of healthy controls. The AS-OCT was used to measure lower tear meniscus parameters (tear meniscus height (TMH), tear meniscus depth (TMD), and tear meniscus area (TMA)), total CT and epithelial thickness

Enrollment

70 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

The inclusion criteria were patients with thyroid disorders with age between 20 to 60 years with no ocular manifestations

Exclusion criteria

being younger than 20 or older than 60, presence of systemic diseases as diabetes mellitus (DM) and autoimmune diseases as rheumatoid arthritis (RA) that may cause dry eye, previous ocular surgery, use of contact lenses, smokers, pregnant women, and breastfeeding women.