ASA- and Clopidogrel-Responsiveness in Patients With Peripheral Arterial Occlusive Disease and Interventional Procedures

Johann Wolfgang Goethe University Hospital

Status: Suspended

Conditions: Peripheral Arterial Occlusive Disease

Study type: Observational

Funder types: Other

Identifiers

NCT00593762

E 19/05

Details and patient eligibility

About

The purpose of the study is to determine the response to aspirin (ASA) and Clopidogrel in patients with peripheral arterial occlusive disease (PAOD) requiring interventional procedures and to investigate if patients with "resistance" to ASA or Clopidogrel have an unfavourable outcome during long-term follow-up

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• PAOD patients
• Age 18-85 years
• Need for a catheter interventional procedure
• Antithrombotic therapy with aspirin or clopidogrel

Exclusion criteria

• Comedication additionally compromising platelet function
• Known bleeding disorder
• Life expectancy < 6 months