Ascorbyl Peroxide Association With Bronchopulmonary Dysplasia

St. Justine's Hospital

Status: Completed

Conditions: Bronchopulmonary Dysplasia

Study type: Observational

Funder types: Other

Identifiers

NCT01439295

CIHR246505 (Other Grant/Funding Number)

University of Montreal

Details and patient eligibility

About

Urinary ascorbyl peroxide level in the first week of life will be a good predictor of Bronchopulmonary dysplasia (BPD) in preterm infants less than 33 weeks of gestation.

Full description

This study uses ascorbyl peroxide as representative of oxidative stress in premature infants on parenteral nutrition and aims to test the correlation of this metabolite and the different major neonatal outcomes 'mainly bronchopulmonary dysplasia).

Enrollment: 51 patients

Sex: All

Ages: 23 to 32 weeks old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Preterm infants less than 33 weeks of gestation<
• Admission to CHU Sainte-JUstien neonatal intensive care unit
• Receiving Parenteral nutrition during the first week of life
• Parental consent

Exclusion criteria

• Major congenital anomalies
• Sever perinatal asphyxia

Trial design

51 participants in 1 patient group

Preterm less than 33 weeks

Description:

This cohort will be composed of premature infants born before 33 weeks of gestational age, admitted to the neonatal intensive care unit at Sainte-Justine hospital and receiving parenteral nutrition (PN) during their first week of life.