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Ashwagandha Supplementation for Prevention of Muscle Damage

U

University of Saskatchewan

Status

Enrolling

Conditions

Muscle Damage

Treatments

Dietary Supplement: Placebo
Dietary Supplement: Ashwagandha

Study type

Interventional

Funder types

Other

Identifiers

NCT06900569
2024_25_06

Details and patient eligibility

About

Ashwagandha is an herbal supplement that has a wide range of benefits related to exercise when supplemented for about 8-12 weeks. This study aims to investigate whether short-term Ashwagandha supplementation can enhance muscle recovery following exercise by measuring muscle strength recovery, swelling, and soreness in the biceps.

Full description

The purpose of the study is to determine the effects of Ashwagandha supplementation on recovery from muscle-damaging exercise. Ten to twenty participants will be randomized to receive Ashwagandha supplementation (600 mg/d) or placebo for 10 days. On day 7, participants will perform a muscle damaging exercise session (six sets of concentric and emphasized eccentric repetitions with the biceps). Before and after exercise and at 24, 48, and 72 hours after exercise, isometric muscle strength, muscle swelling (ultrasound), and muscle soreness will be assessed. The investigators hypothesize the Ashwagandha will alleviate symptoms of muscle damage (swelling and soreness) and enhance strength recovery after a bout of muscle-damaging exercise.

Enrollment

20 estimated patients

Sex

All

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: male or female, aged 18-35y

Exclusion Criteria:

Conditions that may be affected by exercise (determined by "yes" answers to the "Get Active Questionnaire") Pregnant Breastfeeding

Allergies to:

  • Dicalcium Phosphate
  • Cellulose
  • Vegetable magnesium stearate
  • Silica

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

20 participants in 2 patient groups, including a placebo group

Placebo
Placebo Comparator group
Description:
600 mg/d placebo for 10 days
Treatment:
Dietary Supplement: Placebo
Ashwagandha
Experimental group
Description:
600 mg/d Ashwagandha
Treatment:
Dietary Supplement: Ashwagandha

Trial contacts and locations

1

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Central trial contact

Philip Chilibeck

Data sourced from clinicaltrials.gov

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