Asparagus Capsule Consumption and Blood Sugar and Lipids and Oxidative Stress

Burapha University

Status and phase: Completed; Phase 2

Conditions: Asparagus Capsule Consumption

Treatments: Other: Placebo capsule; Dietary Supplement: Asparagus capsule

Study type: Interventional

Funder types: Other

Identifiers

NCT06195813

IRB3-115/2565

Details and patient eligibility

About

Participants were 44 overweight and obese persons, male and female, age 18-59 years. Participants were divided into 2 groups consisting of 23 asparagus capsules and 21 placebo capsules groups. They received health screenings including history taking, mental health questionnaire, and vital signs, height and body weight, body composition, fat distribution measurements and oral glucose tolerance test. Then, a venipuncture was conducted to determine blood glucose, insulin, lipids malondialdehyde and protein carbonyl levels.

Full description

The study design was cross-sectional. Participants were 44 overweight and obese persons, male and female, age 18-59 years. Participants were divided into 2 groups consisting of 23 asparagus capsules and 21 placebo capsules groups. They received health screenings including history taking, mental health questionnaire, and vital signs, height and body weight, body composition, fat distribution measurements and oral glucose tolerance test. Then, a venipuncture was conducted to determine blood glucose, insulin, lipids malondialdehyde and protein carbonyl levels. Analysis of covariance was used to analyze parameters between groups and paired t-test was used to analyze parameters intra-group.

Enrollment: 44 patients

Sex: All

Ages: 18 to 59 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Man or woman, aged between 18 to 59 years
• Body mass index more than 23 (Asian criteria)
• No history of hypertension, diabetes, cardiovascular disease, respiratory disease, endocrine disease, neuromuscular disease, musculoskeletal disease, liver disease, renal disease, immune disease, infectious disease, or cancer
• No regular intake of dietary supplements, i.e., vitamins, antioxidants
• No regular smokers or alcohol drinkers (>2 times per week)
• Not sportman or regular exerciser (>2 times per week or >150 min per week)
• No food allergy, especially shoot

Exclusion criteria

• Current signs or symptoms of infection, i.e., fever, hyperpnea, dyspnea, and palpitations.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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44 participants in 2 patient groups, including a placebo group

Asparagus capsule

Experimental group

Description:

Participants were randomized to receive an arm. In this arm, participants received asparagus capsule and were asked to consume at 40 mg/kg (1-2 capsule) within 15-30 min after breakfast. Consumption was taken at participants' dwelling.

Treatment:

Dietary Supplement: Asparagus capsule

Placebo capsule

Placebo Comparator group

Description:

Participants were randomized to receive an arm. In this arm, participants received placebo capsule and were asked to consume at 40 mg/kg (1-2 capsule) within 15-30 min after breakfast. Consumption was taken at participants' dwelling.

Treatment:

Other: Placebo capsule