Aspiration of Limited Number of Follicles to Prevent Severe Ovarian Hyperstimulation Syndrome

Ahmad Hussieny Salama

Status: Completed

Conditions: Infertility

Treatments: Procedure: 7 eggs collection; Procedure: Full eggs collection

Study type: Interventional

Funder types: Other

Identifiers

NCT02635425

LFOHSS

Details and patient eligibility

About

The purpose of this study is to evaluate the effect of single ovarian puncture to retrieve 7eggs only in prevention of severe ovarian hyperstimulation syndrome.

Full description

Thirty patients will be selected for this study grouped into two groups, each group contains fifteen patients.

Group 1 :study group ( retrieval of 7 eggs only). Group 2 :control group ( retrieval of all eggs). Study is held to compare between the two arms, the proportion of patients who will be prevented from the progression to severe OHSS after this interventional method.

Enrollment: 30 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. More than 9 days of induction of ovulation.
2. Each ovary contains more than 20 follicles.
3. The majority of follicles are >14mm in diameter.
4. Mild fluid in Douglas pouch.
5. The patient started to complain of considerable lower abdominal pains before the egg collection.

Exclusion criteria

1. Recurrent ICSI failure or bad obstetric history.
2. Any medical disorder affecting the fluid shift as: diabetes mellitus, autoimmune diseases, hepatic, renal or cardiac conditions.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

7 eggs collection

Experimental group

Description:

Aspiration of 7 eggs only

Treatment:

Procedure: 7 eggs collection

Full eggs collection

Active Comparator group

Description:

Aspiration of all eggs

Treatment:

Procedure: Full eggs collection