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Assesment of the Metabolomic Signature in COVID-19 Patients (SignCov)

C

Centre Hospitalier Universitaire de Nice

Status

Completed

Conditions

COVID 19

Treatments

Other: COVID-19 patients

Study type

Interventional

Funder types

Other

Identifiers

NCT04497272
20-PP-18

Details and patient eligibility

About

Metabolomics is the analysis of small molecules in a biological sample (cells, tissues or biological fluids). It can potentially detect very sensitively any change related to a pathology or exposure to a toxic agent. The analyses are fast, inexpensive and therefore applicable in routine, particularly in health care. Given the emergence of this new disease, COVID-19, there is a real need to better understand the pathophysiological mechanisms of SARS-CoV-2 infection. In this context, metabolomics could have a place and could lead to the development of interesting diagnostic or prognostic tools. The objective of this study is to identify, through the analysis of biological samples (blood and urine), whether there is a metabolomic signature in patients with COVID-19.

Enrollment

150 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patient over 18 years of age
  • affiliated to a social security scheme
  • consultant in the emergency department and/or being hospitalized for suspected SARS CoV infection
  • confirmation, after medical examination, of the need for a biological examination (this will negate the need for additional venipuncture)

Exclusion criteria

  • Patient who do not meet inclusion criteria
  • Person subject to a guardianship order
  • Opposition to the use of the data or samples (withdrawal of non-opposition) / Sponsor's or investigator's decision

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

150 participants in 1 patient group

The metabolomic signature of COVID-19 patients
Other group
Description:
It will consist in the collection of 1 additional tubes at their blood draw and 1 urine sample.
Treatment:
Other: COVID-19 patients

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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