Assess the Variability of Uni-Dimensional, Bi-Dimensional, and Volumetric CT Scan Measurement of Non-Small Cell Lung Cancer Tumors

Memorial Sloan Kettering Cancer Center (MSK)

Status: Completed

Conditions: Non Small Cell; Lung Cancer

Treatments: Procedure: CT Scan

Study type: Observational

Funder types: Other

Identifiers

NCT00579852

06-149

Details and patient eligibility

About

The purpose of this study is to compare the results of two CT scans of the chest performed within minutes of each other. We will compare several different measurements of lung cancer tumors. This study will help show whether we can get accurate results when we compare measurements on different CT scans. This information is important for patients with cancer, who often have more than one CT scan during their treatment.

Full description

Standard criteria for tumor response assessment have used uni-dimensional or bi-dimensional measurements as a surrogate for volume determination. Modern CT scan techniques, in combination with algorithms developed at MSKCC, allow the calculation of tumor volume. This protocol is designed to evaluate the reproducibility of the calculated volume of pulmonary masses on separate CT scans obtained on the same day in patients with non-small cell lung cancer (NSCLC). Patients with NSCLC undergoing non-contrast CT scan of the chest will have a second, non-contrast CT scan of the chest performed. Uni-dimensional, bi-dimensional, and volume measurements for the primary NSCLC lesion will be determined on both scans and the values compared.

Enrollment: 37 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Have pathologically confirmed non-small cell lung cancer
• Have measurable primary pulmonary tumors ≥ 1cm
• Have plans for a clinically indicated non-contrast CT scan of the chest
• All patients must be ≥ 18 years old

Exclusion criteria

• Pregnant or lactating women

Trial design

37 participants in 1 patient group

1

Description:

Patients with NSCLC undergoing non-contrast CT scan of the chest will have a second, high resolution, non-contrast CT scan of the chest performed on the same day.

Treatment:

Procedure: CT Scan