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Assess Vitamin D Levels in Those With & Without Thyroid Cancer

University of Nebraska logo

University of Nebraska

Status

Completed

Conditions

Thyroid Cancer

Study type

Observational

Funder types

Other

Identifiers

NCT00719615
0136-08-EP

Details and patient eligibility

About

The purpose of this study is to evaluate Vitamin D levels in thyroid cancer patients with active disease compared with thyroid cancer patients in remission and patients with thyroid nodules.

Full description

Thyroid cancer is the most common endocrine related malignancy, increasing in incidence in recent years. There are relatively few, well known factors, both genetic and environmental, which predispose to the development of thyroid cancer. Vitamin D deficiency has been associated with other cancers, but the association between vitamin D and thyroid cancer is unknown. We plan to do a case control, pilot study to evaluate the relationship between vitamin D levels and thyroid nodules, thyroid cancer in remission, and active thyroid cancer.

Enrollment

111 patients

Sex

All

Ages

19+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Cases: History of Papillary, Follicular, Follicular Variant of Papillary, or Hurthle cell thyroid cancer (both active disease and in remission).
  • Controls: Individuals with a thyroid nodule, matched to cases for age, BMI, season of vitamin D measurement.
  • Participating in University of Nebraska Medical Center Thyroid Tumor and Cancer Collaborative Registry database.

Exclusion criteria

  • Pregnant or breast feeding women
  • Medullary thyroid cancer
  • Anaplastic thyroid cancer

Trial design

111 participants in 3 patient groups

Thyroid Cancer in Remission Group
Description:
Thyroid Cancer-Remission Group \& use of Vitamin D
Thyroid Cancer with Active Disease Group
Description:
Thyroid Cancer-Active Group \& use of Vitamin D
Thyroid nodule group (no cancer) & Vit D
Description:
Thyroid nodule group without cancer and use of Vitamin D

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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