Assessing Dietary Requirements in Relation to Resting Metabolic Rate in Spinal Cord Injury

Penn State Health

Status: Completed

Conditions: Dietary Habits; Spinal Cord Injuries

Treatments: Diagnostic Test: Body Composition; Diagnostic Test: Resting Metabolic Rate; Behavioral: Dietary Assessment

Study type: Observational

Funder types: Other

Identifiers

NCT03518892

7333

Details and patient eligibility

About

Assess the relationship between body composition, metabolism, and dietary needs in people with spinal cord injury compared to their healthy controls that are age and sex matched.

Full description

This study will quantify body composition and resting metabolic rate and then compare these parameters to results from a nutritional analysis. Participants will have two study visits that include physical exam, blood draws, resting metabolic rate, Dual Energy X-ray Absorptiometry (DXA) scan, and dietary assessments.

Enrollment: 16 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. C4-L2 motor complete (AIS A & B) Spinal Cord injury for duration greater than 12 months.

2. <5% change in body in body weight over the past 12 months 5. Fluent in written and spoken English

Exclusion criteria

1. <22% body fat
2. Coronary artery disease
3. Type 1 diabetes mellitus, insulin-requiring Type 2 or untreated diabetes mellitus (fasting glucose>126 or HgbA1c>7.0)
4. Hypothyroidism, and/or renal disease
5. Decisional impairment
6. Prisoner

Trial design

16 participants in 2 patient groups

Spinal Cord Injury Group

Description:

Body Composition, Resting Metabolic Rate, and dietary assessment

Treatment:

Behavioral: Dietary Assessment

Diagnostic Test: Resting Metabolic Rate

Diagnostic Test: Body Composition

Healthy Controls

Description:

Body Composition, Resting Metabolic Rate, and dietary assessment

Treatment:

Behavioral: Dietary Assessment

Diagnostic Test: Resting Metabolic Rate

Diagnostic Test: Body Composition