Assessing Gene-Environment Interactions in Clinical Presentation of Nevi and Melanoma

University of Colorado Denver (CU Denver)

Status: Completed

Conditions: Nevi and Melanomas

Treatments: Other: UV Photo; Other: Biological Sample; Behavioral: UV Counseling

Study type: Interventional

Funder types: Other

Identifiers

NCT03783325

16-1603.cc

Details and patient eligibility

About

This research study is designed to better understand the role of genetics, sun-exposure and phenotypic factors in melanoma.

Enrollment: 71 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. > or = 18 years of age
2. Patient at the University of Colorado Anschutz Medical Campus Cutaneous Oncology Clinic or Dermatology Clinic OR attend the fundraising event of the Colorado Melanoma Foundation

Exclusion criteria

1. No exclusion criteria listed

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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71 participants in 3 patient groups

UV Counseling

Other group

Description:

Evaluate the effectiveness of dosimetry feedback on sun exposure behaviors, attitudes, and awareness in patients diagnosed with melanoma.

Treatment:

Behavioral: UV Counseling

Visual Analysis - UV Photo

Experimental group

Description:

Assess the relationships between UV camera score, silicone mold of a skin patch, phenotypic evaluation and sun-exposure behaviors. Technically, this arm is a sub-study that does not involve an intervention. Patients are not receiving an intervention; they are simply providing data to the study team.

Treatment:

Other: UV Photo

Biological Sample

Experimental group

Description:

Determine the relationship between measures of sun exposure and genomic characteristics of tumors in melanoma patients. Technically, this arm is a sub-study that does not involve an intervention. Patients are not receiving an intervention; they are simply providing data to the study team.

Treatment:

Other: Biological Sample