Assessing Lung Dynamics and Respiratory Functions in Minimal Flow Anesthesia: A Prospective Study

Ataturk University

Status: Completed

Conditions: Minimal Flow Anesthesia; Compliance, Patient; Pulmonary Function Test; Medium Flow Anesthesia; Peak Inspiratuar Pressure

Treatments: Other: Minimal flow anesthesia; Other: Medium flow anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT06055335

2/106 25.03.2021

Details and patient eligibility

About

The patients were randomized into two groups medium flow anesthesia (MeFA) and minimal flow anesthesia (MiFA). While MeFA received medium flow anesthesia with 2 lt/min, MiFA received minimal flow anesthesia with 0.5 lt/min fresh gas flow. In both groups dynamic compliance values, peak inspiratory pressure (PIP) values, total inhalation anesthetic drug consumption, total remifentanil drug consumption, duration of anesthesia, and duration of surgery were recorded. The FVC, FEV1, and FEV1/FVC values of the patients in both groups were evaluated and noted 24 hours before the operation, after the operation 2nd, 8th, and 24th hours.

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I-II
• 18-65 years of age, who will undergo elective laparoscopic cholecystectomy surgery

Exclusion criteria

• ASA III-IV
• Smokers
• Body mass index (BMI) > 40 kg / m2,
• Patients with cardiovascular system disease
• Chronic respiratory diseases,
• Patients whose pulmonary function tests cannot be applied and who have problems with pulmonary function tests during the examination of the chest disease consultant

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Medium flow anesthesia

Experimental group

Description:

After reaching the MAC 1 value with 4lt/min 50% O2 - 50% air and 8% desflurane medium flow anesthesia was started with 2 lt/min 50% O2 - 50% air with MAC 1 concentration desflurane.

Treatment:

Other: Medium flow anesthesia

Minimal flow anesthesia

Experimental group

Description:

After reaching the MAC 1 value with 4 lt/min 50% O2 - 50% air and 8% desflurane minimal flow anesthesia was started with 0.50 lt/min 50% O2 - 50% air with MAC 1 concentration of desflurane.

Treatment:

Other: Minimal flow anesthesia