Assessing Perceptual Effects of Interactive Tasks

The Pennsylvania State University (PENNSTATE)

Status: Enrolling

Conditions: Amyotrophic Lateral Sclerosis

Treatments: Behavioral: Listener judgements of speech produced in different tasks

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT06828523

STUDY00024154-2

R01DC021714 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

In this study, we will evaluate how solo, naive listeners perceive the speech of people with amyotrophic lateral sclerosis (ALS) and age-matched speakers produced across interactive and non-interactive contexts with an unfamiliar, naive interlocutor.

Full description

Listeners will hear recorded speech of PALS and age-matched speakers and indicate what they heard. Recorded speech consists of vowels and consonants produced in non-interactive and interactive tasks. The perceptual judgements will be compared to see whether interactive contexts have similar perceptual effects across the two groups.

Plans for Assignment - This is a single group study in which all participants will engage in the same tasks.

Delivery of Intervention: Solo listeners will participate in this study in a remote, asynchronous format. They will be recruited using the online participant recruitment platform Prolific © and will use their own laptop/computer and headphones.

Adequacy of Sample size: We will use n = 1300 listeners to achieve 80% power at alpha of .05 to detect between group differences with the assumption of medium effect sizes (Cohen's f = 0.3).

Adequacy of Analyses: The proposed statistical analyses (Generalized mixed effects regressions) are standard and will be used to analyze the effect of the intervention on the outcome measures described below.

Enrollment: 1,300 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• passing the remote hearing screening
• having no known speech, language or neurological disorders per self-report
• being a native monolingual speaker of American English
• having no experience communicating with people with dysarthria
• being between the ages of 18 and 65.

Exclusion criteria

• None - if volunteer meets the inclusion criteria, then they will be enrolled

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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1,300 participants in 1 patient group

Listener Perception of Speech Produced in Different Task Settings

Experimental group

Description:

Listeners will hear recorded speech of PALS and age-matched speakers produced within interactive and non-interactive contexts and indicate what they heard.

Treatment:

Behavioral: Listener judgements of speech produced in different tasks