Assessing Performance on Speech Tasks Via Crowdsourced Participants (AMYWEB)

Novoic

Status: Terminated

Conditions: Cognitive Impairment; Mild Cognitive Impairment

Treatments: Other: No intervention/exposure

Study type: Observational

Funder types: Industry

Identifiers

NCT05298501

NOV-0300

Details and patient eligibility

About

The purpose of the study is to examine the properties of the Automatic Story Recall Test (ASRT) and its parallel variants, as well as letter fluency and category fluency cognitive tests. Tests will be completed in crowdsourced populations, to derive normative data, and examine test properties in demographically diverse and cognitively impaired participants recruited and tested online.

Full description

The AMYWEB study will validate speech tasks developed by NOVOIC in different population samples, including normative samples, samples recruited for enhanced demographic diversity, and participants with reported cognitive impairment.

Participants will be research volunteers recruited online and via crowdsourcing platforms. Six rounds of recruitment will be completed, evaluating different parallel variants of the Automatic Story Recall Task (ASRT), and fluency tasks. During each recruitment round participants will complete a speech test battery and questionnaires during one assessment (Baseline). Speech tasks will be recorded and later analyzed on Novoic's technology platform. All assessments will be fully online and remote.

Enrollment: 1,034 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• First language must be English
• Residing in the USA
• Willing to participate in a study investigating speech and dementia
• Able to provide informed consent
• Access to personal computing device that is capable of audio and video recording, and able to connect to the internet

Since key research questions are focused primarily on older-age speech and cognition, initial recruitment will be focused on older adult age brackets, which may be extended to younger adulthood if the desired sample sizes are not attained.

Exclusion criteria

• No formal exclusion criteria will apply at the point of recruitment and testing. however, participants with a reported history of neurological conditions or head injury, and current depression will be excluded from normative data development.

Trial design

1,034 participants in 3 patient groups

AMYWEB-Normative

Description:

This cohort assessed over six recruitment and test phases, will be sampled to be as closely representative of the demographic population as possible.

Treatment:

Other: No intervention/exposure

AMYWEB-Diversity

Description:

This cohort assessed over two recruitment and test phases will oversample participants from minority and mixed ethnic and racial backgrounds as well as participants from lower educational backgrounds.

Treatment:

Other: No intervention/exposure

AMYWEB-MCI

Description:

This cohort assessed and recruited over one test phase, will include participants with a reported diagnosis of mild cognitive impairment or dementia.

Treatment:

Other: No intervention/exposure