Assessing the Effects of Air-cooling on Capillary Malformations

National Health Service, United Kingdom

Status: Unknown

Conditions: Skin Cooling; Laser; Capillary Malformation

Treatments: Device: Air cooling to CM site

Study type: Observational

Funder types: Other

Identifiers

NCT01735734

GN

Details and patient eligibility

About

The purpose of this observational study is to ascertain the effects of cutaneous air cooling on vessel diameter within Capillary Malformations (CM).

Full description

Capillary malformation (CM) is the most common vascular malformation occurring in approximately 0.3% of all newborn. The standard treatment for facial or aesthetically sensitive CM's is flashlamp Pulsed Dye Laser. Skin cooling prior to laser treatment of CMs is standard practice within our department. The effects of skin cooling on the vasculature within CMs are poorly understood. Previous studies by our department have shown that raising ambient temperature increases CM vessel size. It has been postulated that by increasing CM vessel size, it may also increase the effectiveness of treatment. We hypothesize that cooling the skin during laser treatment may cause vasconstriction of the superficial vessels within the CM. This may have an impact on treatment success.

Enrollment: 35 estimated patients

Sex: All

Ages: 16+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult more than 16 years of age
• Patient diagnosed with Capillary Malformation

Exclusion criteria

• Patients less than 16 years of age

Trial design

35 participants in 1 patient group

Capillary malformation

Treatment:

Device: Air cooling to CM site