Assessing the Symptoms of Obstructive Sleep Apnea (OSA)

Bangor University

Status: Completed

Conditions: Obstructive Sleep Apnea

Study type: Observational

Funder types: Other

Identifiers

NCT01481636

Earing 11/WNo01/2 (Other Identifier)

REC No: 11/WNo:01/2

Details and patient eligibility

About

The purpose of this study is to investigate the correlation between health outcomes associated with the severity of obstructive sleep apnea (OSA) symptomatology, the findings will guide the design of interventional studies.

Full description

Obstructive sleep apnea is a condition characterised by periods of narrowing of the pharyngeal airways during sleep causing hypoxic and hypercapnic episodes with the cessation of ventilation. Considering the high number of overweight and obese individuals in Western society the understanding of the pathomechanisms behind OSA are important. This observational study aims to investigate the correlations between the severity of Obstructive Sleep Apnea assessed by the apnea-hypopnea index (AHI) and different health outcomes associated with the OSA.

Enrollment: 66 patients

Sex: Male

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Body Mass Index ≤39
• Not received any treatment for Obstructive Sleep Apnea.
• Is a non-smoker
• Is not epileptic
• Epworth Sleepiness Scale ≥ 10.
• Patient's on Statins or antihypertensive drugs are included as so frequent in OSA.

Exclusion criteria

• Body Mass Index ≥ 39.
• Presence of significant or unstable Renal, Liver or Heart Failure.
• Receiving anti-diabetic treatment.
• Is a smoker.
• Is epileptic
• Presence of significant or unstable psychological morbidities.

Trial design

66 participants in 1 patient group

No treatment, OSA (AHI >15)

Description:

Patients with OSA recruited prior to receiving NHS treatment.