Assessing the Utility of Ultrasound Compared to Cross-Sectional Imaging in the Follow-up of Patients With Renal Cell Carcinoma

University of Kansas

Status: Unknown

Conditions: Renal Cell Carcinoma

Treatments: Diagnostic Test: Ultrasonography

Study type: Interventional

Funder types: Other

Identifiers

NCT04424472

STUDY00145327

Details and patient eligibility

About

The aim of this study is to determine the utility of renal ultrasonography (US) in the detection of abdominal recurrences after definitive therapy for renal cell carcinoma (RCC) and compare the detection rate to that of cross-sectional imaging.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients must be 18 year of age or older.
• Patients having undergone radical or partial nephrectomy for the indication of renal cell carcinoma.
• Most recent imaging study must have been either computed tomography (CT) or magnetic resonance imaging (MRI).

Exclusion criteria

• Patients with pT4 disease (tumor invades beyond the Gerota fascia: including contiguous extension into the ipsilateral adrenal gland).
• Patients with metastatic disease prior to time of surgery requiring systemic treatment.
• Patients with another active cancer diagnosis requiring systemic treatment.
• Patients with contrast allergies.
• Patients with baseline chronic kidney disease (GFR < 45 ml/min/1.73 m2).

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

Ultrasonography

Experimental group

Description:

Patient will be scheduled to undergo an additional US by a blinded sonographer within 4 weeks of their most recent cross-sectional imaging that indicated a recurrence

Treatment:

Diagnostic Test: Ultrasonography