Assessment of a Pre-Workout Dietary Supplement (NB1)

Texas A&M University

Status: Completed

Conditions: Dietary Modification

Treatments: Dietary Supplement: C4 Extreme; Dietary Supplement: C4 Extreme (without Advantra Z; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT02952014

IRB2014-0022FX

Details and patient eligibility

About

The purpose of this study is to examine the acute effects of a pre-workout dietary supplement on energy metabolism, cardiovascular hemodynamics, blood metabolites and mental focus.

Full description

A number of nutritional strategies have been developed to optimize nutrient delivery prior to exercise. This includes providing carbohydrate and a number of ergogenic nutrients prior to, during and/or following exercise. As a result a number of pre-workout supplements have been developed to increase energy availability, promote vasodilation and/or positively affect exercise capacity. The purpose of this study is to investigate the potential ergogenic value of acute ingestion of a pre-workout dietary supplement prior to exercise.

Enrollment: 31 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• you are an apparently healthy and recreationally active man or woman between the ages of 18 and 40;
• you will need to have at least six months immediate prior history of resistance training on the bench press and leg press or squat;

Exclusion criteria

• you have a history of treatment for metabolic disease (i.e., diabetes), hypertension, hypo-tension, thyroid disease, arrhythmia and/or cardiovascular disease;
• you are currently using prescription medications;
• you have an intolerance to caffeine and/or other natural stimulants;
• you are pregnant or a lactating female or plan to become pregnant with the next month;
• you have a history of smoking;
• you drink excessively (i.e., 12 drinks per week or more);

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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31 participants in 3 patient groups, including a placebo group

C4 Extreme

Experimental group

Description:

One dose of 12 grams (powder mixed with water): 1500 mg beta alanine, 1000 mg creatine nitrate, 1000 mg arginine AKG, 250 mg vitamin C, 150 mg n-acetyle tyrosine, 135 mg caffeine, 7.5 mg l-dopa, 30 mg vitamin B3, 10 mg synephrine, 0.5 mg vitamin B6, 0.25 mg vitamin B9, 0.035 mg vitamin B12.

Treatment:

Dietary Supplement: C4 Extreme

C4 Extreme (without Advantra Z)

Active Comparator group

Description:

One dose of 12 grams (powder mixed with water): 1500 mg beta alanine, 1000 mg creatine nitrate, 1000 mg arginine AKG, 250 mg vitamin C, 150 mg n-acetyle tyrosine, 135 mg caffeine, 7.5 mg l-dopa, 30 mg vitamin B3, 0.5 mg vitamin B6, 0.25 mg vitamin B9, 0.035 mg vitamin B12.

Treatment:

Dietary Supplement: C4 Extreme (without Advantra Z

Placebo

Placebo Comparator group

Description:

One dose of flavored placebo (powder mixed with water)

Treatment:

Dietary Supplement: Placebo