Assessment of Bone Quality and Quantity for Three Dimensional Bone Augmentation for Maxilla Using Patient Specific Titanium Meshes Loaded With Bone Marrow Aspirate Mixed With Xenograft Versus Xenograft Mixed With Autografts Only: a Randomized Clinical Trial

Cairo University (CU)

Status: Unknown

Conditions: Atrophic Maxilla

Treatments: Procedure: Three dimensional maxillary bone augmentation

Study type: Interventional

Funder types: Other

Identifiers

NCT05400044

1222

Details and patient eligibility

About

Assessment of bone quality and quantity for three dimensional bone augmentation for maxilla using titanium meshes loaded with bone marrow aspirate mixed with xenograft versus xenograft mixed with autografts only

Enrollment: 20 estimated patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients are free from any systemic conditions and bone metabolic diseases that might interfere with the surgical intervention, soft tissue or hard tissue healing.

  • Edentulous anterior or posterior maxilla with deficient alveolar ridge that is less than 5 mm measured from the crest of the alveolar ridge to the nasal or maxillary sinus and less than 4mm in buccolingual width.
  • The minimum number of missing teeth in the alveolar ridge is two adjacent teeth.

Exclusion criteria

• Intra-bony lesions (e.g. cysts) or infections (e.g. abscess) that may retard the osteotomy healing.

  • Previous grafting procedures in the edentulous area.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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20 participants in 2 patient groups

bone marrow aspirate mixed with xenograft

Experimental group

Treatment:

Procedure: Three dimensional maxillary bone augmentation

xenograft mixed with autografts only:

Active Comparator group

Treatment:

Procedure: Three dimensional maxillary bone augmentation